In the course of the at present evolving outbreak of monkeypox instances outdoors of identified endemic areas, transmission is principally pushed by shut bodily contact with symptomatic folks. Whereas virus transmission between people has been described beforehand, information on environmental contamination of surfaces are uncommon.
Environmental sampling in affected person rooms
Nörz et al. swabbed surfaces within the fast and adjoining rooms of two hospitalised monkeypox sufferers in Germany. The sufferers’ isolation rooms had been separated from the ward hall by anterooms, the place hospital workers put their private protecting gear on and off (donning and doffing).
Contamination with as much as 105 viral copies/cm2 on inanimate surfaces was estimated by PCR and the virus was efficiently remoted from surfaces with greater than 106 copies.
In response to the authors, all of the surfaces that the 2 sufferers had touched instantly confirmed viral contamination, with the best hundreds detected in each loos (e.g. lever, washbasin, rest room seats). Materials akin to towels, shirts or pillowcases that the sufferers used steadily additionally confirmed viral contamination.
Viral contamination doesn’t equal infectious virus
The authors spotlight that there at present are not any particular information on what dose of virus results in an infection with monkeypox in people. Nevertheless, assumptions are that it requires a considerably greater dose to set off an infection than e.g. variola virus.
Nörz et al. therefore stress that “regardless of excessive contamination with as much as 105 cp/cm2 in addition to the profitable restoration of monkeypox virus from samples with a complete of >106 copies, our findings don’t show that an infection can happen from contact with these surfaces”. Moreover, detecting viral DNA by PCR “can’t be equated with infectious virus”.
Prevention of virus unfold from symptomatic sufferers must be individually tailored. Based mostly on their findings, the authors conclude that “common disinfection of frequent hand and pores and skin contact factors through the care processes extra to common room cleansing and floor disinfection utilizing merchandise with no less than virucidal exercise in opposition to enveloped viruses can cut back infectious virus on surfaces and thereby danger of nosocomial transmission”.
Nörz, D., et al. (2022) Proof of floor contamination in hospital rooms occupied by sufferers contaminated with monkeypox, Germany, June 2022. Eurosurveillance. doi.org/10.2807/1560-7917.ES.2022.27.26.2200477.