Man’s ‘overzealous’ vitamin D use led to overdose, hospitalization



After months of nausea and vomiting, a middle-age man in the UK lastly realized the poisonous reason for his well being issues: an excessive amount of vitamin D. His medical doctors discovered that an overzealous complement routine was responsible.

The affected person misplaced 28 kilos (12.7 kilograms) in three months and complained to his normal practitioner of persistent stomach ache, dry mouth, diarrhea and vomiting, in response to a case examine printed July 6 within the British Medical Journal. On the hospital, medical doctors realized that the person’s signs had began about one month after he started an intense vitamin routine steered by a personal nutritionist.

Underneath the routine, the affected person had been taking 150,000 worldwide models (IU) of vitamin D day by day — 250 occasions the 600 IU really helpful by the Mayo Clinic. And he was ingesting greater than 20 different dietary supplements on high of that, together with greater than the really helpful quantity of omega-3, vitamin K2 and folate. Excessive ranges of serum creatine, a waste product that wholesome kidneys remove from the body entirely, confirmed the affected person’s kidneys had been affected. The person recovered after receiving intravenous fluid for rehydration, and being hospitalized for eight days as his kidneys recovered. 

Associated: Why you can’t skip magnesium if you’re taking vitamin D

“A typical false impression with dietary dietary supplements, together with vitamin D, is that if some is nice, then taking extra is best,” Shelby Yaceczko, a complicated follow scientific dietitian on the Middle for Human Vitamin on the College of California, Los Angeles, who was not concerned within the case report, advised Stay Science in an e mail. “Sadly, that’s not the case and though it is vital to take care of regular vitamin ranges, it is also crucial to keep away from taking larger doses than what is taken into account protected.” 

Mega-dosing nutritional vitamins may be dangerous, in response to Yaceczko. An excessive amount of vitamin D within the physique can result in signs reminiscent of drowsiness, vomiting, weak point, constipation, bone ache and irregular coronary heart rhythm. Routine blood work is the one technique to precisely establish and proper dietary deficiencies, Yaceczko mentioned. With out this sort of monitoring, sufferers grow to be in danger for toxicities, just like the one seen within the case examine. (The case examine did not point out if the affected person was having routine blood work executed by his nutritionist, and the report’s authors weren’t out there for remark).

Nonetheless, there could also be one thing else at play, in response to Dr. Heather Tick, a scientific affiliate professor of household drugs and an endowed professor of integrative drugs on the College of Washington in Seattle, who was not concerned with the case report. “All the pieces he was on — it was loads of stuff,” she advised Stay Science. However “often you’ll want to be taking excessive doses of vitamin D for for much longer, not only a month” to expertise toxicity, Tick added. 

In response to Yaceczko, scientific literature means that “vitamin D toxicity can occur between 1 [to] 4 months relying on a number of elements in addition to the mega-dose amount the person is taking.”

Tick additionally mentioned it is attainable that the affected person within the case examine could have had an underlying situation that “predisposes him to build up vitamin D.”

Tick added that it is vital to notice that medical doctors in standard drugs could harbor a bias towards dietary supplements and parts of integrative drugs, and that might be at play within the case examine’s conclusions. 

Yaceczko, who’s a registered dietician, additionally warned that the time period “nutritionist” is usually used loosely, is an unregulated title and does not require any type of schooling or work expertise. Folks ought to due to this fact train warning about the place they get their vitamin recommendation and hunt down medical professionals who’ve undergone the required coaching, Yaceczko mentioned.

Initially printed on Stay Science.

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