Information present reasonable safety in infants born to COVID-vaccinated mothers
Maternal COVID vaccination throughout being pregnant gives 52% safety towards COVID-19 hospitalization in infants however solely 38% safety towards Omicron hospitalization, in response to a research yesterday within the New England Journal of Drugs.
Safety towards an intensive care unit (ICU) keep, nevertheless, was 70%.
The case-control research included 537 case infants (181 hospitalized for COVID-19 in the course of the Delta interval and 356 throughout Omicron) and 512 management infants who didn’t have COVID. The median age of each teams was 2 months, and 19% of the case infants and 24% of the management infants had a minimum of one underlying well being situation.
Among the many case infants, 113 (21%) required intensive care, 64 of whom obtained mechanical air flow or vasoactive infusions. Two infants born to unvaccinated moms died from COVID-19.
The researchers decided that the effectiveness of maternal vaccination with two doses of mRNA vaccine towards hospitalization for COVID-19 in infants total was 52% (95% confidence interval [CI], 33% to 65%), however fell from 80% (95% CI, 60% to 90%) throughout Delta to 38% (95% CI, 8% to 58%) throughout Omicron. Effectiveness was 69% (95% CI, 50% to 80%) for vaccination after 20 weeks of being pregnant and 38% (95% CI, 3% to 60%) for earlier within the being pregnant.
Safety was 70% (95% CI, 42% to 85%) towards admission to an ICU and 47% (95% CI, 25% to 62%) towards non-ICU hospitalization.
In a associated editorial, Sonja Rasmussen, MD, from the College of Florida, and Denise Jamieson, MD, MPH, from Emory College, stated, “This proof that Covid-19 vaccines assist to guard infants in addition to moms is extremely related for affected person counseling: a ‘two-for-one’ deal could encourage extra moms to obtain Covid-19 vaccination.”
A letter in the identical journal, in the meantime, particulars no enhance in critical occasions amongst 45,232 pregnant ladies who had obtained one or two doses of a COVID vaccine instantly earlier than or throughout being pregnant. The info are from eight US Vaccine Security Datalink websites from ladies vaccinated from Dec 15, 2020, by way of Jul 1, 2021.
Jun 22 N Engl J Med study, editorial, and letter
1 in 5 US adults expertise COVID-19 signs 3 months after an infection
A brand new survey of US adults exhibits 1 in 5 have skilled lingering signs of COVID-19 which have persevered for a minimum of 3 months, suggesting lengthy COVID is a typical phenomenon after acute an infection.
The survey was carried out by the US Census Bureau this month, and outcomes had been analyzed by the Facilities for Illness Management and An infection (CDC). Forty % of these polled stated that they had been contaminated with COVID-19, with 1 in 13 of all US adults experiencing lengthy COVID signs on the time they had been surveyed. These signs can embody mind fog, headache, and muscle ache.
The US reported 184,074 new COVID-19 instances yesterday and 860 deaths, in response to the Johns Hopkins COVID-19 tracker. The 7-day common of latest each day instances is 97,069, with 298 each day deaths, in response to the New York Occasions tracker.
As vaccines for the youngest Individuals at the moment are out there, Tennessee lawmakers are urging Gov Invoice Lee to delay the state’s well being division from distributing and selling the COVID-19 vaccines to youngsters below 5, the Related Press (AP) experiences.
CDC specialists votes to advocate high-dose flu vaccines for seniors
Yesterday the CDC’s Advisory Committee on Immunization Practices (ACIP) unanimously beneficial the usage of high-dose influenza seasonal vaccine for Individuals 65 years and older, owing to the waning immunity seen on this age-group with standard-dose vaccines.
That is the primary time the group has beneficial a sure flu vaccine for these 65 and older.
At present there are three such vaccines available on the market, Fluzone Excessive-Dose, Fluad with an immune booster, or Flublok, which is made with insect cells as an alternative of hen eggs, AP experiences.
Sanofi, which makes Fluzone, launched a brand new survey this week displaying that 66% of US healthcare suppliers would advocate high-dose flu vaccines to senior sufferers