Information Scan for Sep 02, 2022

CDC director endorses up to date COVID booster suggestion

Quickly after vaccine advisors to the Facilities for Illness Management and Prevention (CDC) yesterday voted to advocate up to date COVID boosters that focus on the unique virus plus the Omicron BA.4 and BA.5 subvariants, CDC Director Rochelle Walensky, MD, MPH, endorsed the Advisory Committee on Immunization Practices (ACIP) suggestion, paving the best way for immunization to start.

In a press release, she mentioned the advice adopted a complete scientific analysis and a strong dialogue.

“The up to date COVID-19 boosters are formulated to raised defend in opposition to essentially the most not too long ago circulating COVID-19 variant,” she mentioned. “They can assist restore safety that has waned since earlier vaccination and had been designed to offer broader safety in opposition to newer variants. This suggestion adopted a complete scientific analysis and sturdy scientific dialogue.”

The CDC recommends the brand new Pfizer/BioNTech booster for these ages 12 and older and the brand new Moderna booster for these ages 18 and up. For each teams, the CDC recommends receiving the booster a minimum of 2 months after receiving the first vaccine collection or the final booster dose. Walensky mentioned, “If you’re eligible, there isn’t a unhealthy time to get your COVID-19 booster and I strongly encourage you to obtain it.”

In associated developments, the White Home is making ready to ask Congress for $22.4 billion to fund the COVID-19 response and $3.9 billion for the monkeypox response, The Hill reported right this moment, citing administration sources. The COVID funding is for short-term wants corresponding to testing, analysis and growth of next-generation vaccines and medicines and help for international efforts.

Yesterday throughout the CDC vaccine advisory panel discussions, a CDC official signaled that current funding will cowl the rollout of the up to date boosters with a provide of 171 million doses. The funding request for COVID-19 is just like the $22.5 billion emergency funding that the Biden administration requested within the spring however didn’t obtain.
Sep 1 CDC statement
Sep 1 CIDRAP news story
Sep 2 Hill story

Preschoolers’ father or mother confidence in COVID vaccines wanes as security proven

Right this moment in Morbidity and Mortality Weekly Report (MMWR), survey outcomes present that parental confidence in COVID-19 vaccines dipped after authorization for preschoolers, and surveillance reveals that the majority opposed occasions after mRNA vaccination on this age-group had been delicate or reasonable.

A crew led by researchers from the College of Arizona and the CDC studied the intent of 393 mother and father of kids aged 4 months to 4 years to vaccinate their kids in opposition to COVID-19 from July 2021 to Could 2022. The Pfizer/BioNTech and Moderna mRNA vaccines had been approved for this age-group on Jun 17, 2022. The survey was a part of an ongoing examine in Arizona, Florida, Texas, and Utah.

At baseline, 64.4% of fogeys mentioned they had been more likely to vaccinate their kids, whereas 19.3% had been unsure and 9.9% had been unlikely. Three months later, mother and father had been 16% much less more likely to vaccinate their kids (adjusted odds ratio [aOR], 0.84) and 39% and 35% much less more likely to suppose the vaccines had been efficient (aOR, 0.61) and protected (aOR, 0.65), respectively. Each intent to vaccinate and notion of security rose considerably 6 months after baseline, however the findings weren’t vital after adjustment.

“Enhanced efforts to deal with parental confidence in childhood vaccination and improve vaccination protection amongst kids aged <5 years are wanted, together with reinforcing the effectiveness and security of vaccination in opposition to COVID-19,” the researchers wrote.

In one other examine, CDC researchers monitored native and systemic opposed occasions reported to v-safe and the Vaccine Opposed Occasion Reporting System (VAERS) after Pfizer or Moderna vaccination in kids aged 6 months to five years from Jun 18 to Aug 21, 2022.

Amongst 1,040,230 vaccinees, most opposed occasions had been delicate or reasonable. VAERS acquired 1,017 adverse-event experiences, 98.1% of them nonserious, and there have been no experiences of myocarditis (irritation of the center muscle).

“Well being care suppliers and oldsters of younger kids must be conscious that native and systemic reactions are anticipated after vaccination with Pfizer-BioNTech or Moderna vaccine and that critical opposed occasions are uncommon,” the authors wrote.
Sep 2 MMWR parental intent study and mRNA vaccine study


CDC experiences extra E coli with hyperlinks to romaine on Wendy’s sandwiches

The CDC yesterday reported 13 extra diseases in an Escherichia coli O157:H7 outbreak which may be tied to romaine lettuce served on Wendy’s sandwiches, with two extra affected states—Kentucky and New York.

The brand new developments push the outbreak whole to 97 individuals in 6 states. To date, 43 individuals have been hospitalized, and 10 had hemolytic uremic syndrome (HUS), a doubtlessly deadly kidney complication. The newest sickness onset was Aug 15.

State and native well being officers are nonetheless interviewing sick individuals concerning the meals they ate earlier than they turned ailing. Of 67 individuals with detailed meals histories, 54 (81%) ate at Wendy’s the week earlier than in eating places situated in Indiana, Michigan, Ohio, and Pennsylvania. They’d eaten a wide range of menu objects, together with sandwiches and burgers.

Investigators are nonetheless analyzing different components as a possible supply of the outbreak. Wendy’s makes use of a unique supply of romaine for its sandwiches than it does for its salads, and as a precaution it has eliminated the romaine it makes use of for sandwiches.
Sep 1 CDC outbreak update


Midwestern states see return of high-path avian flu in poultry

4 Midwestern states—Indiana, Minnesota, North Dakota, and Wisconsin—reported extra avian flu outbreaks in poultry flocks, a part of a small however regular stream of occasions over the summer season.

The Indiana State Board of Animal Well being (BOAH) mentioned birds in a pastime flock in Elkhart County examined presumptive constructive for H5 avian influenza. The power has 261 chickens, geese, and geese, which had been depopulated. The outbreak is the state’s first since Jun 8.

In the meantime, the Minnesota Board of Animal Well being (MBAH) has reported two new outbreaks at turkey farms in Meeker County, the state’s first since Could. The 2 central Minnesota areas housed 174,849 birds. Additionally, the MBAH reported an outbreak involving 20 yard birds in Hennepin County, which is within the Twin Cities.

Shauna Voss, DVM, senior veterinarian with the MBAH, mentioned, “Whereas the timing of this detection is a bit prior to we anticipated, now we have been making ready for a resurgence of the avian influenza we handled this spring.”

Additionally, North Dakota reported an outbreak in a yard flock of 20 birds in Cass County, its first since Jun 6, in response to an replace from the US Division of Agriculture (USDA) Animal and Plant Well being Inspection Service (APHIS).

Right this moment, the Wisconsin Division of Agriculture, Commerce, and Shopper Safety (DATCP) reported an outbreak in a yard flock in Washington County, the primary since Could.

In associated US developments, APHIS reported three extra outbreaks from three not too long ago affected California counties. Two contain business farms, together with a broiler breeder in Fresno County housing 22,900 birds and a turkey farm in Tuolumne County that has 30,800 birds. Additionally, APHIS reported an outbreak in Sacramento County involving a flock of 10 yard birds.

To date, outbreaks in america involving the extremely pathogenic H5N1 pressure have led to the lack of 40.8 million birds throughout 39 states.
Aug 30 Indiana BOAH update
Aug 31 MBAH press release and avian flu updates
Sep 2 Wisconsin DATCP statement
USDA APHIS poultry outbreak updates

Europe has additionally reported H5N1 outbreaks in poultry over the summer season months, with Portugal the most recent to report one other occasion involving business poultry. In accordance with a notification from the World Group for Animal Well being (WOAH), the virus struck a fattening duck farm that has 47,868 birds in Evora, about 85 miles east of Lisbon.
Sep 2 WOAH report on H5N1 in Portugal



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